Physician Information Packet
Get an information packet sent to your office!
Counting Methodology and Sensitivity
PVSA is the most sensitive mail-in kit on the market. As the original mail-in test kit, we’ve been perfecting this process for more than 30 years.
Better Quality Results
The PVSA kit’s patented fixative stabilizes the semen specimen and eliminates the time sensitivity between sample collection and analysis.
In addition to stabilizing the specimen, the fixative introduces a predictable dilution factor. When this is applied to hemacytometry, the resulting detection threshold becomes:
3,300 sperm per milliliter of semen
This threshold is at least 10x more sensitive than standard methods used in clinics, home tests or other mail-in kits.
At this level of precision, sperm motility becomes irrelevant (2022 report). Even non-motile sperm are detected and quantified, providing physicians and patients with the most reliable analysis of post-vasectomy status.
Method Sensitivity Comparison
| Method | Threshold Sensitivity |
|---|---|
| In-office (40X microscopy) | ~250,000 sperm/mL |
| CASA (Computer-Assisted) | ≤100,000 sperm/mL |
| Sample competitor: SpermCheck® (Home Test) | 250,000 motile sperm/mL |
| PVSA™ (Lab-Based Method) | 3,300 sperm/mL |
Backed by Expertise
This methodology is based on more than 30 years of laboratory experience and continuous refinement of semen analysis protocols. PVSA’s approach is detailed in the 2022 PVSA Report, and was developed under the direction of our Lab Director, Ann A. Kiessling, a board-certified specialist in andrology whose work has been published in multiple peer-reviewed journals.

Two options to integrate PVSA into your practice:

Patient Self-Ordering
Office-Managed Ordering
Easy for Doctors
Easy for Patients

Patient compliance you can count on
87%
of men using PVSA mail-in kits return specimen
96%
report PVSA is “easy
Request a Phyisician Information Packet for your Office
We’ll send your information pack within 1-2 business days. Please don’t hesitate to call or email with any questions in the meantime: 617.623.7447 | lab@bedfordresearch.org
Your Choice Supports Independent Science
PVSA kits were first developed for NIH-funded research and now continue to support ongoing investigations into men’s health. A portion of profits goes to support our non-profit research partner Bedford Research Foundation.
Anderson Biotest is an independent company with over 30 years of expertise. Our CLIA-certified lab publishes in peer-reviewed journals and reinvests profits into research. See our list of publications
We are patient-first, science-first, and focused on delivering top-quality tests at affordable prices.

Specialized Mail-In Kit
PVSA kits have easy to follow instructions (pdf).
Patented Fixative
PVSA uses a patented fixative that preserves the semen specimen for analysis, which means the specimen is not time-sensitive and can be sent via regular mail. Techniques and instrumentation (pdf)

CLIA Certified Lab Results
Laboratory Test Protocol (pdf)
